MesKit - A tool kit for dissecting cancer evolution from multi-region
derived tumor biopsies via somatic alterations
MesKit provides commonly used analysis and visualization
modules based on mutational data generated by multi-region
sequencing (MRS). This package allows to depict mutational
profiles, measure heterogeneity within or between tumors from
the same patient, track evolutionary dynamics, as well as
characterize mutational patterns on different levels. Shiny
application was also developed for a need of GUI-based
analysis. As a handy tool, MesKit can facilitate the
interpretation of tumor heterogeneity and the understanding of
evolutionary relationship between regions in MRS study.